Mélanie Henderson , M.D. , Ph.D. , FRCPC
    Mélanie Henderson
    Research Axis
    Metabolic and Cardiovascular Health Axis
    Research Theme
    Cardiometabolic and vascular health: from genetics to environmental approaches
    CHUSJ - Centre de Recherche

    514 345-4931 #3604


    • Deputy Head, Research Axis, Metabolic and Cardiovascular Health, CHU Sainte-Justine Research Center 
    • Pediatric Endocrinologist, CHU Sainte-Justine
    • Clinical Assistant Professor, Department of Pediatrics, Faculty of Medicine, Université de Montréal


    • PhD, Science Epidemiology, Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, 2014
    • M.Sc., Science Clinical Epidemiology, University of Toronto, 2007
    • Pediatric endocrinology residency, Université de Montréal, 2006
    • Pediatric endocrinology residency, University of Toronto, 2005
    • Pediatric residency, University of Toronto, 2003
    • Medicine, McGill University, 1999
    • BSc, Science Occupational Therapy, Université de Montréal, 1995

    Research Interests

    My research interests focus on the etiology of obesity, its metabolic and cardiovascular consequences, and their prevention in various populations, including healthy children, as well as children with diabetes mellitus. I am particularly interested in the influence of lifestyle habits on metabolic health in youth. Understanding how physical activity, sedentary behaviour, diet and sleep influence metabolic health is critical to developing effective preventive strategies for clinical practice and public health alike. I am also interested in the evaluation of such novel strategies in the prevention or treatment of cardiovascular disease risk in childhood.

    Research Topics

    • Pediatrics
    • Obesity
    • Type 2 diabetes
    • Lifestyle habits
    • Cardiovascular disease
    • Epidemiology

    Awards and Distinctions

    • Career Enhancement Program Award - Canadian Child Health Clinician Scientist Program
    • Chercheur-boursier - Junior 1 - Volet Clinique et Épidémiologie - Fonds de recherche du Québec - Santé (FRQS)
    • CIHR Fellowship - Canadian Institutes of Health Research
    • Scholarship matching funds - CHU Sainte Justine
    • Doctoral Research Award - Fonds de recherche du Québec - Santé (FRQS)


    Pediatric Intervention Centre for Heart Disease Prevention and Rehabilitation (CIRCUIT) 

    Video clips Mon ÉquiLibre

    Devrait-on s’inquiéter du poids de son enfant? (in French only)

    Est-ce normal que l’appétit de son enfant varie d’une journée à l’autre? (in French only)


    • Fitzpatrick C, Datta G, Henderson M, Gray-Donald K, Kestens Y, Barnett T. (2017). School food environments associated with adiposity in Canadian children. International Journal of Obesity.
    • Michaud I, Henderson M, Legault L, Mathieu, ME. (2017). Physical activity and sedentary behaviour levels in children and adolescents with type 1 diabetes using insulin pump or injection therapy - The importance of parental activity profile. Journal of Diabetes and Its Complications. 31(2): 381-386.
    • Jabbour G, Tremblay A, Henderson M, Mathieu ME. (2017). Mechanical efficiency in children with different body weights – A longitudinal assessment of the QUALITY cohort. Biology of Sport. 34: 71-76.
    • Pelaez S, Alexander S, Henderson M, Roberge J-B, Bigras J-L, Barnett T. (2016). ‘Life in the age of screens’: parent perspectives on a 24-hour no screentime challenge. Clinical Obesity. 6(4): 273-280.
    • Bird M, Datta GD, van Hulst A, Cloutier M-S, Henderson M, Barnett T. (2016). A Park Typology in the QUALITY Cohort: Implications for Physical Activity and Truncal Fat among Youth at Risk of Obesity. Preventive Medicine. 90: 133-138.
    • Nguyen S, Haecker AL, Henderson M, Barnett TA, Mathieu ME, Pagani LS, Bigras, JL. (2016). Physical activity programs with post-intervention follow-up in children: a comprehensive review according to categories of intervention. International Journal of Environmental Research and Public Health. 13(7): 664-680.
    • Brazeau A-S, Nakhla M, Wright M, Panagiotopoulos C, Pacaud D, Henderson M, Rahme E, DaCosta D,
    • Dasgupta K. (2016). Stigma and its impact on glucose control among youth with diabetes, a Canada-Wide Study. JMIR Research Protocols. 5(4): e242.
    • Jabbour G, Henderson M, Mathieu ME. (2016). Barriers to an active lifestyle in children with type 1 diabetes. Canadian Journal of Diabetes. 40(2): 170-172.
    • Henderson M, Benedetti A, Barnett T, Mathieu ME, Deladoëy J, Gray-Donald K. (2016). The influence of adiposity, physical activity, fitness and screen time on insulin dynamics over 2 years in youth. JAMA Pediatrics. 170(3): 227-235.
    • Setayeshgar S, Maximova K, Ekwaru JP, Gray-Donald K, Henderson M, Paradis G, Tremblay A, Veugelers PJ. (2016). Diet quality as measured by the Diet Quality Index-International is associated with prospective changes in body fat among Canadian children. Public Health Nutrition. Sep 23: 1-8.
    • Wilke MS, Maximova K, Henderson M, Levy E, Paradis G, O'Loughlin J, Tremblay A, Proctor SD. (2016). Adiposity in Children and CVD risk: ApoB48 has a stronger association with central fat than classic lipid markers. The Journal of Clinical Endocrinology & Metabolism. 101(7): 2915-2922.
    • Solomon-Krakus S, Sabiston CM, Brunet J, Castonguay AL, Maximova K, Henderson M. (2016). Body image self-discrepancy and depressive symptoms among early adolescents. Journal of Adolescent Health. 61): 38-43.
    • Gallant A, Lundgren J, O’Loughlin J, Allison K, Tremblay A, Henderson M, Drapeau V. (2015). Night eating symptoms and two year weight change in parents enrolled in the QUALITY cohort. International Journal of Obesity. 39(7): 1161-1165.
    • Shang L, Wang JW, O'Loughlin J, Tremblay A, Mathieu ME, Henderson M, Gray-Donald K. (2015). Screen Time is Associated with Dietary Intake in Overweight Canadian Children. Preventive Medicine Reports. 2015(2): 265-269.
    • Delvin E, Patey N, Dubois J, Henderson M, Lévy E. (2015). Pediatric Non-Alcoholic Fatty Liver Disease. Journal of Medical Biochemistry. 34(1): 3-12.
    • Jabbour G, Henderson M, Tremblay A, Mathieu ME. (2015). Aerobic Fitness Indices of Children Differed Not by Body Weight Status But by Level of Engagement in Physical Activity. J Phys Act Health. 12(6): 854-860.
    • Côté-Lussier C, Jackson J, Kestens Y, Henderson M, Barnett TA. (2015). A Child's View: Social and Physical Environmental Features Differentially Predict Parent and Child Perceived Neighborhood Safety. J Urban Health. 92(1): 10-23.
    • Van Hulst A, Roy-Gagnon M-H, Gauvin L, Kestens Y, Henderson M, Barnett TA. (2015). Identifying risk profiles for childhood obesity using recursive partitioning based on individual, familial, and neighborhood environment factors. International Journal of Behavioral Nutrition and Physical Activity. 12(February): 17-25.


    1. Henderson M, Benedetti A, Barnett T, Mathieu ME, Deladoëy J, Gray-Donald K. (2016). The influence of adiposity, physical activity, fitness and screen time on insulin dynamics over 2 years in youth. JAMA Pediatrics. 170(3): 227-235.
    2. Henderson M, Benedetti A, Gray-Donald K. (2014). Dietary composition and its associations with insulin sensitivity and insulin secretion in youth.The British Journal of Nutrition. 111(3): 527-534.
    3. Henderson M, Gray-Donald K, Rabasa-Lhoret R, Bastard JP, Barnett TA, Benedetti A, Chaput JP, Tremblay A, Lambert M. (2014). Insulin secretion and its association with physical activity, fitness and screen time in children.Obesity (Silver Spring, Md.). 22(2): 504-511.
    4. Henderson M, Baillargeon JP, Rabasa-Lhoret R, Chiasson JL, Hanley J, Lambert M. (2012). Estimating insulin secretion in youth using simple indices derived from the oral glucose tolerance test.Diabetes & Metabolism. 38(4): 309-315.
    5. Henderson M, Gray-Donald K, Mathieu ME, Barnett TA, Hanley JA, O'Loughlin J, Tremblay A, Lambert M. (2012). How are physical activity, fitness, and sedentary behavior associated with insulin sensitivity in children?. Diabetes Care. 35(6): 1272-1278.

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