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Centre de recherche

Friday 6 September 2019 from 12:00 at 13:00

Scientific Conference of Friday Noon

Quantitative medicine for rational diagnostics, treatment, and therapy personalization

Speaker

  • Morgan Craig, PhD
    • Assistant Professor, Department of Mathematics and Statistics, University of Montreal

To better design, develop, and administer therapies, we must discern the physiological mechanisms (pathological or not) regulating drug effects. Quantitative medicine, an emerging field integrating (patho)physiology, pharmacometrics, mathematics/statistics, and computational biology/machine learning, allows us to translate from mechanism to disease to therapy to answer foundational questions about how diseases develop, how to address disorders as they progress, and how best to stay healthy. 

This talk will highlight three major axes of my research dealing with how we understand and treat hemato-immune disorders, and leverage immune mechanisms as therapies. I will discuss how I use computational biology in complement with experimental and clinical data to 1) understand healthy hemato-immune regulation to identify pathophysiological mechanisms of rare blood disorders, 2) rationalize the treatment of HIV with long-acting agents, and 3) translate from mechanism to therapy to personalize cancer immunotherapy.

 
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Updated on 9/12/2019
Created on 8/19/2019
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